Pattern of Polyphenol Intake and the Long-term Risk of Dementia in Older Persons
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,329
- 主要终点
- incidence of dementia
研究概览
简要总结
This project aims to leverage existing data from a large observational prospective study on dementia, the Three-City study, to investigate the relationship between intakes of polyphenols and the risk to develop dementia in the 12 years following dietary assessment.
详细描述
The study sample includes 1,329 subjects followed for up to 12 years fro dementia after dietary assessment. The aim is to identify a pattern of polyphenol intake (based on 26 flavonoid and non-flavonoid polyphenol subclasses ascertained using a 24-hour dietary recall) associated with the risk of dementia and AD over 12 years in the 3C Bordeaux cohort.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •65 years or more, live in Bordeaux area (France)
排除标准
- •with dementia at the time of dietary assessment in year 2001-2002
结局指标
主要结局
incidence of dementia
时间窗: 12 years
incident cases of dementia diagnosed by the expert committee of neurologists at follow-up visits
次要结局
- incidence of Alzheimer's disease(12 years)
研究者
Jean-François Dartigues
Pr
University of Bordeaux