The Effects of Secondary Smoking to Intraoperative Arterial Oxygen Tension During One Lung Ventilation in Lobectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- intraoperative peak airway pressure
研究概览
简要总结
Smoking and perhaps secondary smoking is associated with many perioperative and postoperative complications, especially respiratory events. Hypoxemia and airway damage can be associated with secondary smoking. The aim of study is to predict the incidence of hypoxemia and airway damage during one lung ventilation for lobectomy.
详细描述
Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube will be included in this study. These patients will be divided into 2 groups. Groups S which will be included non smoking and secondary smoking and group SS which will be included secondary smoking ( smoking near him more than 10 cigarettes per day fore more than 5 years). Intra and postoperative arterial oxygen tension, arterial carbon dioxide tension and intraoperative peak airway pressure will be compared between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Investigator)
入排标准
- 接受健康志愿者
- 否
入选标准
- •Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube, ASA physical status 2 and 3.
排除标准
- •Recent chest infection, morbid obesity, renal, hepatic and ischemic hearts disease, asthma.
研究组 & 干预措施
Group S (non smoking and secondary smoking)
I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.
干预措施: One Lung Ventilation (Other)
Group SS (secondary smoking)
I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.
干预措施: One Lung Ventilation (Other)
结局指标
主要结局
intraoperative peak airway pressure
时间窗: during intraoperative ventilation
arterial oxygen tension
时间窗: From beginning of Anesthesia to 1st day of surgery
arterial carbon dioxide tension
时间窗: From beginning of Anesthesia to 1st day of surgery
次要结局
未报告次要终点