A randomised controlled trial of patient-directed self-management of pain (PaDSMaP) compared to treatment as usual following total knee replacement.

orfolk and Norwich University Hospital NHS Trust (UK)0 个研究点目标入组 144 人开始时间: 2012年3月22日最近更新: 2018年6月11日

试验速览

•1. All adult patients (e.g. aged over 18) undergoing a primary total knee replacement operation
•2. Must meet the Norfolk and Norwich University Hospital NHS Foundation Trust self-management of pain criteria
•3. Are expected to require standard step 1-3 oral analgesics post-operatively (WHO 2009)
•4. Post-operatively, patients must be awake and breathing independently, able to answer questions and follow commands to continue in the protocol
•5. Are English speaking and literate (we expect patient participants to be able to read the information sheet and fill in a number of self-assessments)
•6. Patients may have received regional blocks or epidural analgesia, and will start PaDSMaP or TAU as soon as they begin oral analgesia

•1. Expected to require intensive care
•2. Known or suspected to be opioid tolerant or dependent
•3. Regular users of any modified release opiate preparation for > two weeks prior to total knee replacement
•4. Recent history of drug or alcohol abuse
•5. Patients who lack competence to consent by reason or dementia or any other reason
•6. Any patient who does not self-administer at home

发起方

orfolk and Norwich University Hospital NHS Trust (UK)