Evaluation of Bifidobacterium Animalis Spp. Lactis oral suspension effect on crying/fussing time and changes of gut microbiota in formula-fed infants with colic: A Double blind randomized clinical trial

Ramsar Campus, Mazandaran University of Medical Sciences0 个研究点目标入组 50 人开始时间: 待定最近更新: 2019年3月25日

适应症

试验速览

暂无简介。

•birth weight lower than 2500grams
•preterm birth (Gestational age<37 weeks)
•five minute Apgar score <7
•breast feeding
•Central venous catheter
•severe medical condition
•valvular heart disease
•prematurity
•reduction in growth or weight reduction of more than 100gram from birth to the last measurement
•neurological disease
•known of suspected food allergy
•gastroesophageal reflux disease
•Probiotic, prebiotic, antibiotic or acid suppressing agents in the past two weeks
•history of fever or infectious disease in the past two weeks
•progressive systemic infection
•congenital infection
•chronic bowel disease, e.g. cystic fibrosis and primary pancreatic insufficiency
•primary or secondary digestive tract malformations, e.g. esophageal atresia, intestinal atresia, short bowel syndrome, malrotation
•metabolic disease
•genetic and chromosomal disease
•primary or secondary immunodeficiency syndrome
•suspecting noncompliance or caregiver's inability to act in accordance to the given protocol
•previous participation in medical research

发起方

Ramsar Campus, Mazandaran University of Medical Sciences