Sensory Rehabilitation in Chemotherapy Induced Peripheral Neuropathy (CIPN)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- FABS
研究概览
简要总结
Physiotherapist research about Sensory rehabilitation in chemotherapy induced peripheral neuropathy (CIPN) with the aid of questioners and physiotherapy practice
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 and over who suffer from chemotherapy-induced neuropathy (CIPN), according to the patient's report, more than 3 months since the end of the chemotherapy treatment.
排除标准
- •Sensory damage / neuropathy that existed even before the start of chemotherapy
- •Incidents of recurrent falls even before the start of chemotherapy (over 2 falls for 6 months)
- •Central nervous system involvement
- •Major pre-morbid orthopedic lower limb impairment
- •Hebrew language not sufficient for assessment and treatment
研究组 & 干预措施
Explicit sensory retraining for lower extremity in individuals with CIPN
Explicit sensory retraining for lower extremity function (pain, sensory, balance, gait). five one-hour sessions, a week apart: Pre-Post assessment sessions with 3 treatment sessions in between. Home exercise assigned.
干预措施: Questionares and practice (Diagnostic Test)
结局指标
主要结局
FABS
时间窗: 2 years
Fullerton Advanced Balance Scale: high function balance test - consisting of 10 activities in both static and dynamic phases; 10-40, higher scores are better.
LEPT
时间窗: 2 years
Lower Extremity Position Test: proprioception detection and quantification
TNAS
时间窗: 2 years
TNAS -Treatment-Induced Neuropathy Assessment Scale. 0-90. higher score = worse status
VAS
时间窗: 2 years
0-100 mm visual scale: self-reporting pain assessment from no pain to worst pain possible. We will ask for current pain and the worst pain during the last week.
Allodynia
时间窗: 2 years
tested by non-painful mechanical stimulation: gentle brushing and monofilament
NSA
时间窗: 2 years
Nottingham Sensory Assessment: sensory detection and discrimination test
Semmes-Weinstein monofilament testing
时间窗: 2 years
tactile detection threshold
TUG
时间窗: 2 years
Timed Up and Go: fall prediction screening test; measures time taken to raise from a chair walking 3 meters and re-sit.
次要结局
未报告次要终点
研究者
Rotem Merose
Breast Oncologist
Assaf-Harofeh Medical Center