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临床试验/CTRI/2024/09/073705
CTRI/2024/09/073705已完成2/3 期

Open label single arm clinical study on the combined efficacy of gomutra haritaki vati and nalpamaradi taila in dadru (Dermatophytosis)

Sri Dharmasthala Manjunatheswara College of Ayurveda and Hospital Hassan1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年10月1日最近更新:

试验速览

阶段
2/3 期
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
Kandu (Itching) , Raga (Erythema).

研究概览

简要总结

The symptoms of Dadru are closely resembles with symptoms of Dermatophytosis (Tinea). Dermatophytes are the most frequent causative agents of superficial fungal infections, which affects keratinized tissue3. As India being a tropical country, there has been a rise in chronic and relapsing dermatophytosis which shown the prevalence of 65.3% and 34.6% respectively4. The infection rates were highest among the age groups involved in occupational and outdoor activities due to the increased exposure to fungal pathogens from the environment and increased perspiration, both predispose to fungal infection5. The present state of dermatophytosis has emerged as a social, psychological and economic burden on the society.

Dadru is a Kapha-Pitta pradhana vyadhi with Kandu, Raga, Pidaka and Mandala. So necessitating the use of medicines have Tikta, Kashaya rasa & property such as Dadrughna, Kandughna or Kushtaghna. Gomutra Haritaki vati has Dadrughna property & Nalpamaradi taila has Kandughna and Kushtaghna property

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Participants suffering with Dadru up to 1 year of duration.
  • 2.Participants of either gender.
  • 3.Participants aged between 18-60 years.
  • 4.Participants willing to participate in the study and ready to sign informed consent form.

排除标准

  • Participants with Tinea mannus, Tinea pedis, Tinea unguium (Onychomycosis).
  • 2.Participants with known case of uncontrolled Diabetes Mellitus (HbA1C greater than 8).
  • 3.Participants with known case of Sexually Transmitted Diseases.
  • 4.Patient taking any immune suppression drugs.
  • 5.Pregnant women.
  • 6.Lactating mother.

结局指标

主要结局

Kandu (Itching) , Raga (Erythema).

时间窗: 14 days

1.Assessment will be based on the symptoms

时间窗: 14 days

2.Pidaka (Eruption) , Mandala (Annular patches) , Centrifugal lesion , Well-demarcated border

时间窗: 14 days

次要结局

  • 1.Pidaka.(2.Size of Mandala.)

研究者

发起方
Sri Dharmasthala Manjunatheswara College of Ayurveda and Hospital Hassan
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

DR Raj Maheshbahi Patel

Sri Dharmasthala Manjunatheswara College of Ayurveda and Hospital Hassan

研究点 (1)

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