Evaluation of the Influence of Bed Rest After Embryo Transfer in Outcome of IVF Treatment With Ovum Donation.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 240
- 试验地点
- 2
- 主要终点
- Live birth infant rate after delivery from both groups of study
研究概览
简要总结
A comparative study to determine whether bed rest after embryo transfer (ET) affects on IVF (In Vitro Fertilization)outcome. This study includes 240 patients undergoing IVF treatment with donated oocytes. All the procedures of IVF, of the embryo transfer, and of the administration of medications are performed as always and there are no variations. The only highlighted procedure in this study is immediately after the embryo transfer. There are two groups: one which will rest in bed for 10 minutes after the transfer and one which will not rest after the transfer. Both procedures are common, usually depending on the habitual clinical practice of each clinic internationally. Patients from both group receive the routine post transfer instructions and treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 49 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Infertile Patients with fertility problems due to tubaric or ovarian problems with normozoospermatic couple
- •Patient and her couple with ages between ages 20 - 49 years old
- •BMI < 25 kg/m2
- •IVF treatment with oocyte donation
- •Elective transfer of 2 embryos of day 3 embryos or day 5/6 embryos transferred
- •First cycle of embryo transfer
排除标准
- •Patients with uterine abnormalities, significant uterine fibroids, Hydrosalphinx
- •History of recurrent pregnancy loss
- •severe male factor were excluded from the study
研究组 & 干预措施
Bedrest
Patients will rest in bed ten minutes after the embryo transfer.
干预措施: Bed rest (Behavioral)
No bed rest
Patients will not rest after the embryo transfer.
干预措施: No bedrest (Behavioral)
结局指标
主要结局
Live birth infant rate after delivery from both groups of study
时间窗: 10 months
Whether bed rest after embryo transfer affects the pregnancy rate in IVF treatment with oocyte donation.
次要结局
- Cranial perimeter of live newborn infant after delivery(10 months)
- Miscarriage rate(5 months)
- Birth weight of live newborn infant after delivery(10 months)
- Birth height of live newborn infant after delivery(10 months)
- Implantation rate(2 months)
- APGAR score of live newborn infant after delivery(10 months)
研究者
Jose Remohi
Gynecologist IVI Valencia
Instituto Valenciano de Infertilidad, IVI VALENCIA