Randomized, flexible-dose, open-label comparison to investigate the effectivenes of second generation antipsychotics in first episode psychosis patients. - second generation antipsychotics in first episode psychosis patients

Dr. Benedicto Crespo. Servicio Psiquiatría. Hospital Universitario Marqués de Valdecilla/IDIVA0 个研究点目标入组 200 人开始时间: 2014年6月9日最近更新: 2014年8月28日

适应症

试验速览

暂无简介。

•From May 2014 to May 2016 all referrals to PAFIP were screened for patients who met the following criteria: 1) 15-60 years; 2) living in the catchment area; 3) experiencing their first episode of psychosis; 4) no prior treatment with antipsychotic medication or, if previously treated, a total life time of adequate antipsychotic treatment of less than 6 weeks; 5) DSM-IV criteria for brief psychotic disorder, schizophreniform disorder, schizophrenia, or schizoaffective disorder. The diagnoses were confirmed using the Structured Clinical Interview for DSM-IV (SCID ?I) (First et al., 2001) carried out by an experienced psychiatrist 6 months on from the baseline visit. Our operational definition for a ?first episode of psychosis? included individuals with a non-affective psychosis (meeting the inclusion criteria defined above) who have not received previously antipsychotic treatment regardless the duration of psychosis.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 200
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Patients were excluded for any of the following reasons: 1) meeting DSM-IV criteria for drug dependence, 2) meeting DSM-IV criteria for mental retardation, 3) having a history of neurological disease or head injury.

发起方

Dr. Benedicto Crespo. Servicio Psiquiatría. Hospital Universitario Marqués de Valdecilla/IDIVA