Effectiveness of Dexamethasone With Lignocaine for Alleviation of Tinnitus
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 264
- 试验地点
- 1
- 主要终点
- Tinnitus relief
研究概览
简要总结
Objective: To determine the effectiveness of Intratympanic dexamethasone with lignocaine in control of idiopathic tinnitus.
Methodology: 264 consenting patients with idiopathic unilateral tinnitus presenting at ENT Department were assessed for tinnitus severity using Modified Tinnitus Handicap Inventory and the scores recorded and subsequently administered intratympanically 2.0 ml (milliliter's) of dexamethasone and lignocaine (1.5 ml dexamethasone + 0.5 ml 1% lignocaine). The dose was repeated twice at weekly intervals. All patients were re assessed on Modified Tinnitus Handicap Inventory two weeks after third Intratympanic administration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •score 20 or above on modified tinnitus handicap inventory
排除标准
- •head trauma, tympanic membrane perforation, depression, ear surgery
研究组 & 干预措施
Dexamethasone with lignocaine
干预措施: Dexamethasone (Drug)
结局指标
主要结局
Tinnitus relief
时间窗: 2 weeks
Tinnitus relief ascertained by Modified Tinnitus Handicap Inventory
次要结局
未报告次要终点
研究者
FARAH AFZAL
CLASSIFIED SPECIALIST
Combined Military Hospital, Pakistan