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临床试验/NCT07038499
NCT07038499尚未招募不适用

Prevalence and Determinants of Migraine Among Headache Patients

Universiti Tunku Abdul Rahman1 个研究点 分布在 1 个国家目标入组 158 人开始时间: 2025年6月23日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
158
试验地点
1
主要终点
Prevalence of migraine

研究概览

简要总结

Migraine is a prevalent and disabling neurological condition that often coexists with other health issues, such as hypertension and impaired physical, mental, and social functioning. Understanding the prevalence of migraine and its associations with these health domains can provide valuable insights into the broader impact of migraine on overall well-being. By focusing on patients at the Affiliated Hospital of Hebei University of Engineering in China, this study can identify specific health burdens within this population, inform integrated clinical management strategies, and support the development of targeted interventions to improve patient outcomes and quality of life.

详细描述

Migraine is a common and disabling neurological disorder that poses a significant public health burden worldwide. In China, the estimated prevalence of migraine is approximately 9.3%, with higher rates reported among women and individuals of working age. Despite being one of the most prevalent types of primary headache disorders, migraine remains underdiagnosed and undertreated in many regions of China, partly due to limited awareness and access to specialized care. Concurrently, hypertension is highly prevalent in the Chinese adult population, with nearly one in four adults affected, making it a leading contributor to cardiovascular morbidity. Emerging evidence suggests a potential bidirectional relationship between migraine and hypertension, possibly linked through shared pathophysiological mechanisms such as endothelial dysfunction, autonomic dysregulation, and inflammatory pathways.

Moreover, migraine is often associated with detrimental effects on physical, mental, and social health, including impaired physical function, increased pain intensity, depression, anxiety, fatigue, sleep disturbances, and reduced ability to participate in social roles and activities. However, studies exploring these multidimensional impacts in Chinese clinical populations remain limited.

Therefore, this study aims to investigate the prevalence of migraine and its association with hypertension as well as physical, mental, and social health domains among headache patients at the Affiliated Hospital of Hebei University of Engineering, China.

研究设计

研究类型
Observational
观察模型
Ecologic Or Community
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients diagnosed with headache according to the International Classification of Headache Disorders, 3rd Edition (ICHD-3).

排除标准

  • Patients with other major diseases or severe mental disorders;
  • History of endocrine, immune, or nervous system diseases or other severe somatic diseases.

结局指标

主要结局

Prevalence of migraine

时间窗: Day 1

The overall number and proportion of people with migraine (according to the International Classification of Headache Disorders, 3rd edition (ICHD-3))

次要结局

  • Correlation with hypertension(Day 1)
  • Correlation with physical (physical function, pain intensity), mental (depression, anxiety, fatigue, sleep disturbance) and social (ability to participate in social roles and activities)(Day 1)
  • Correlation with migraine disability(Day 1)
  • Correlation with quality of life(Day 1)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Foo Chai Nien

Assiociate Professor

Universiti Tunku Abdul Rahman

研究点 (1)

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