JPRN-UMIN000038129已完成未知
Epigenome-wide association study identifies a novel DNA methylation in patients with severe aortic valve stenosis - Epigenome-wide association study identifies a novel DNA methylation in patients with severe aortic valve stenosis
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 188
研究概览
简要总结
EWAS revealed that DNA methylation of a CpG site differed significantly between the AS group and controls. The DNA methyltion level of chromosome 8 position 126448033, which is located at TRIB1 (tribbles homolog 1), was lower in the AS group than in the controls
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- ot applicable 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •clinical signs of acute coronary syndrome, acute infection, severe renal failure (serum creatine levels over 3 mg/dL) or rheumatoid disease, or if they were suspected of having a malignant or primary wasting disorder
研究者
相似试验
已完成
不适用
CpG methylation is a relevant epigentic modification in sepsishealthy subjectsDRKS00012965niversitätsklinikum Knappschaftskrankenhaus Bochum20
已完成
不适用
DNA Methylation Analysis in Acute Coronary Syndrome and Atrial Fibrillation: DIANA Clinical TrialAtrial FibrillationAcute Coronary SyndromeCoronary Artery DiseaseNCT04371809University of Campania "Luigi Vanvitelli"100
Unknown
不适用
DNA Methylation and Arsenic-associated Urothelial CarcinomaUrothelial CarcinomaNCT01360723China Medical University Hospital600
已完成
不适用
Epigenomic Dysregulation in Preeclampsia-Associated Chronic HypertensionPreeclampsiaPregnancy Induced HypertensionHypertensionNCT01682304Ohio State University12
已完成
不适用
Israeli Multi Ethnic Centenarian ProjectLONGEVITY 1NCT03541460Rambam Health Care Campus124