Effects of Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease (COPD)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- 6-Minute walking distance
研究概览
简要总结
The additional effect of inspiratory muscle training as an adjunct to a general exercise training program in patients with COPD with inspiratory muscle weakness will be studied. The main hypothesis is that inspiratory muscle training combined with an exercise training program improves functional exercise capacity more than an exercise training program without the addition of an inspiratory muscle training program.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with COPD
- •Eligible to participate in an inpatient pulmonary rehabilitation program of 3 weeks
- •Pi,max <60 centimeters of water or <50% of the predicted normal value
排除标准
- •Major comorbidities preventing successful participation in an 8 week exercise training intervention
- •use of non-invasive ventilation
研究组 & 干预措施
Inspiratory Muscle Training
Procedure: Inspiratory Muscle Training Three times daily inspiratory muscle training (2x30 breaths) at an intensity of >50% Pi,max
干预措施: Inspiratory Muscle Training (Other)
Sham Inspiratory Muscle Training
Twice daily inspiratory muscle training (3x30 breaths) at an intensity of 5 centimeters of water (H2O)
干预措施: Inspiratory Muscle Training (Other)
结局指标
主要结局
6-Minute walking distance
时间窗: change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program
次要结局
- exercise capacity (constant work rate test)(change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program)
- maximal inspiratory pressure (PImax)(change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program)
- inspiratory muscle endurance capacity(change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program)
- dyspnea(change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program)
研究者
Klaus Kenn
MD
Schön Klinik Berchtesgadener Land