Evaluation of the Effects of Medicaments Used After Free Gingival Graft on Postoperative Complications.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Landry's Wound Healing Index (WHI)
研究概览
简要总结
In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting (FGG).
详细描述
In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting. The effectiveness of these 3 different commercially available agents containing flurbiprofen, hyaluronic acid, and hypochlorous acid, after use 2., 4.7. and on the 14th day, wound healing and pain perception was compared with the control group. primary observation was obtained by visual analog scale, wound healing index, bleeding of tissue, color match, and amount of painkiller used by the patient were also recorded
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with systematic conditions are classified as The American Society of Anesthesiologists Class I
排除标准
- •Pregnancy, lactation, and taking contraceptive pills.
- •Oversensitivity or anaphylactic reactions which contraindicate the intervention.
- •Orofacial neurological symptoms.
- •Infections at operation zone.
- •Psychotropic medicine, sedative, or non-steroid anti-inflammatory drugs use which can alter the sense of pain.
- •Pathological mental conditions (dementia, psychosis) and lack of cooperation.
- •Excessive gag reflex
- •Operations are carried out with conscious sedation.
- •Patients who do not want to sign consent.
研究组 & 干预措施
Control
Patients were not given anything after FGG.
干预措施: Free gingival graft harvesting (Procedure)
Flurbiprofen
Oral spray containing 0.075 g flurbiprofen administered after FGG
干预措施: Majezik %0.25 oral spray (Drug)
Flurbiprofen
Oral spray containing 0.075 g flurbiprofen administered after FGG
干预措施: Free gingival graft harvesting (Procedure)
Hypochlorous acid
Oral spray containing hypochlorous acid applied after FGG
干预措施: Crystalin oral spray (Other)
Hypochlorous acid
Oral spray containing hypochlorous acid applied after FGG
干预措施: Free gingival graft harvesting (Procedure)
Hyaluronic acid
An oral spray containing the main component of the product is hyaluronic acid (sodium salt) with a high molecular weight of 30 mg / 100 g was given to patients after FGG
干预措施: Aftamed oral spray (Other)
Hyaluronic acid
An oral spray containing the main component of the product is hyaluronic acid (sodium salt) with a high molecular weight of 30 mg / 100 g was given to patients after FGG
干预措施: Free gingival graft harvesting (Procedure)
结局指标
主要结局
Landry's Wound Healing Index (WHI)
时间窗: 21 days
WHI was performed on the basis of postoperative healing characteristics categorized as tissue color, response to palpation, incision margins, and suppuration.
次要结局
- Visual Analogue Scale(21 days)
- Color match(21 days)
- delayed bleeding(21 days)
- burning sensation(21 days)
- complete epithelization(21 days)
研究者
AYSAN LEKTEMUR ALPAN
Associate Profesor
Pamukkale University