Development and Clinical Validation of Ketogen-based Therapeutic Diet for Pancreaticobiliary Cancer Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Food Intake Rate(%) for postoperative diet
研究概览
简要总结
Decreased bowel function and loss of appetite in patients who underwent pancreaticobiliary surgery contribute impaired nutritional status in postoperative period. It can also affect perioperative and oncologic outcomes negatively. Therefore it is important to improve nutritional status in postoperative period by supply tailor-made optimal diets. The investigators have developed customized postoperative diets for pancreaticobiliary cancer patients. The investigators expect that customized diets for pancreaticobiliary patients will increase the food intake rate and contribute a improvement of perioperative outcomes and even oncologic outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult (age more than 19)
- •Pancreaticobiliary cancer patient who is scheduled pancreaticoduodenectomy or distal pancreatectomy
- •Pancreatic cancer / Duodenal cancer / Distal bile duct cancer / Ampulla of Vater cancer
排除标准
- •Patient who denied clinical trial
- •Diabetes Mellitus(DM) patient with DM complication
- •Hyperlipidemia patient with vascular co-morbidity
- •Impaired renal function or renal failure (GFP<90%)
研究组 & 干预措施
Ordinary Diet
Ordinary Diet
干预措施: Ordinary Diet (Dietary Supplement)
Modified Atkin's Diet
Modified Atkin's Diet
干预措施: Modified Atkin's Diet (Dietary Supplement)
Ketogenic Diet
Ketogenic Diet
干预措施: Ketogenic Diet (Dietary Supplement)
结局指标
主要结局
Food Intake Rate(%) for postoperative diet
时间窗: 3 days after the diet
Diet Intake Rate(%) will be examined by dietary satisfaction questionnaires.
次要结局
未报告次要终点