Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- genetic risk screening tool (GRST) questionnaire
研究概览
简要总结
To identify Black individuals who are eligible for genetic testing through trusted community organizations, and to connect Black individuals and their families to genetic testing and counseling so that they can know their cancer risk and how to decrease it.
详细描述
Primary Objectives:
- To identify 300 Black families, at least one individual per family, eligible for genetic testing using our validated simple genetic risk screening tool (GRST) 1, via collaboration with trusted community organizations. For individuals eligible for genetic testing, we will counsel them about genetic testing, including reviewing GRST results, explaining why they are eligible for genetic testing as part of standard-of-care, explaining what this entails, offering on-site or remote genetic testing, and explaining that they will be connected to a genetic counselor if they have a pathogenic mutation (PV) of a variant of unknown significance (VUS), including resources for family cascade genetic testing.
- To provide genetic testing to 150 Black individuals and families and provide genetic counseling and risk reduction resources to individuals with a PV or VUS, including cascade genetic testing for their family members.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Any participant over 18 years old who self-identifies as Black or African-American and signs an informed consent form, also referred to as the 'Permission to Contact' form, to be part of our study.
排除标准
- 未提供
研究组 & 干预措施
Genetic Testing and Counseling
Participants will be given a saliva collection kit to collect a saliva sample for hereditary cancer and genetic testing.
干预措施: Genetic Testing and Counseling (Behavioral)
Screening Form
Participants will complete a screening form to assess your risk of hereditary breast and colorectal cancers. You will be asked to provide your:
- Name and contact information (including your address, phone number, and email)
- Demographic information (including your age, race, and ethnicity)
- Health insurance status
- Annual household income
- Personal and family history of cancer, including diagnosis and age at diagnosis
干预措施: Screening Form (Behavioral)
结局指标
主要结局
genetic risk screening tool (GRST) questionnaire
时间窗: through study completion; an average of 1 year.
次要结局
未报告次要终点
