Houston Emergency Engagement System for Youths and Adolescents

The University of Texas Health Science Center, Houston1 个研究点分布在 1 个国家目标入组 250 人开始时间: 2021年4月19日最近更新: 2025年10月1日

适应症

干预措施

试验速览

阶段: 4 期
状态: 招募中
发起方: The University of Texas Health Science Center, Houston
入组人数: 250
试验地点: 1
主要终点: Patient abstinence from opioids

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral counseling, and peer recovery support. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use disorder. The investigators also intend to understand the prevalence of opioid overdoses and OUD among youth in Houston.

详细描述

The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a non-randomized cohort study based at the University of Texas Health Science Center of Houston. This study recruits participants through three avenues: assertive community outreach with a peer coach and paramedic following and opioid overdose, community referrals, and emergency department referrals. The study explores the effect of the combination of assertive outreach, same-day induction into medication for opioid use disorder, ongoing maintenance treatment, behavioral counseling, peer recovery support, and paramedic follow-up on patient outcomes. The primary outcome is engagement and retention in outpatient treatment. Secondary outcomes include quality of life assessment as well as subsequent relapses and overdoses. The hypothesis is that patients with earlier induction into MOUD treatment who receive routine follow-up, are more likely to engage and remain in treatment long-term.

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: 13 Years 至 17 Years（Child）
性别: All
接受健康志愿者: 否

入选标准

•In otherwise good health based on physician assessment and medical history
•Drug screen positive for opioids
•Patients express a willingness to stop opioid use
•Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR) criteria for opioid dependence
•Patients must be able to speak English
•Be agreeable to and capable of signing the informed consent and assent (parent or guardian must consent, minor must assent)

排除标准

•Non-English-speaking patients
•Have a known sensitivity to buprenorphine or naloxone
•Be physiologically dependent on alcohol, benzodiazepines, or other drugs of abuse that require immediate medical attention. Other substance use diagnoses are not exclusionary.
•Have a medical condition that would, in the opinion of the study physician, make participation medically hazardous, including unstable cardiovascular disease, neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease)
•Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an immediate suicide risk
•Be a nursing or pregnant female