Relationship Between Galectin-3 Level and Disease Activity in Ankylosing Spondylitis Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 主要终点
- Relationship Between Galectin-3 Level and Disease Activity in Ankylosing Spondylitis Patients
研究概览
简要总结
Forty-five AS patients and 35 healthy controls were enrolled in this study. Patients diagnosed with AS according to Modified New York criteria were included in the study. Clinical and laboratory measurements, duration of symptoms, age and body mass index (BMI) of AS patients were performed and compared with age and BMI matched control group.
详细描述
Detailed histories of all participants were obtained, and systemic and rheumatologic examinations were performed. We excluded all participants who had a history of hyperlipidemia, liver, renal, hematological, familial thyroid, neoplastic, autoimmune infectious diseases and receiving anti-inflammatory drugs.
We measured serum galectin-3 levels using a commercial chemiluminescent microparticle immunoassay. The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) was used to assess disease activity in AS patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ankylosing spondylitis patients
- •Healthy controls
排除标准
- •Hyperlipidemia
- •Liver diseases
- •Renal diseases
- •Hematological diseases
- •Familial thyroid diseases
- •Neoplastic diseases
- •Autoimmune infectious diseases
- •Receiving anti-inflammatory drugs.
结局指标
主要结局
Relationship Between Galectin-3 Level and Disease Activity in Ankylosing Spondylitis Patients
时间窗: 5 months
Correlation
次要结局
未报告次要终点
研究者
Gul Devrimsel
Clinical Professor
Recep Tayyip Erdogan University Training and Research Hospital