Serum Klotho Level in Patients on Oral Antidiabetic Treatment
试验速览
- 阶段
- 不适用
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Beneficial effect manifested by a statistical significant decrease in klotho levels
研究概览
简要总结
Klotho is a protein found in serum, kidney,heart,brain and in other tissues,it has many functions,it is viewed as the anti aging hormone. Aging kidneys are characterized by progressive scarring and measurable declines in renal function
详细描述
Objectives To study serum klotho level among diabetic patients attending diabetes and endocrine clinic in Fayoum university on oral antidiabetic treatment
Study Design:
This study will be an observational prospective cohort study. The study duration will be 2 months.
Study Methods:
- Population of Study
- Group 1 :compare serum klotho levels in patients taking glimeperirde versus levels in patients taking metformin
- Group 2 : compare serum klotho levels in patients taking glimeperirde versus levels in patients taking linagliptin
- Group 3 : compare serum klotho levels in patients taking glimeperirde versus levels in patients taking impaglifluzin
- Inclusion Criteria :
- Group 1 :Diabetics candidate for oral treatment
- Group 2 :Diabetics candidate for oral treatment
- Group 3 :Diabetics candidate for oral treatment
- Exclusion Criteria :
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diabetics candidate for oral treatment
排除标准
- •Diabetics candidate for insulin treatment
结局指标
主要结局
Beneficial effect manifested by a statistical significant decrease in klotho levels
时间窗: 2 months
An anticipated statistical significant decrease in klotho level
次要结局
- No beneficial effect manifested by by a non significant decrease in klotho level or a rise in the level(2 months)
研究者
Ahmed Abdelkawi Hammad
Lecturer of internal medicine,faculty of medicine,Fayoum university
Fayoum University