Effect of Specific Diet and Circuit-based Exercise on Weight and/or Fat Loss
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- A Body weight change after specific weight loss intervention
研究概览
简要总结
The main purpose of this study is to assess metabolic effects (decreased amount of body fat content, insulin sensitivity and lipid profile improvement) of weight loss intervention based on specific life style counseling (low calorie "metabolic stairs" diet and circuit-based exercise in a comparison to conventional diet and exercise. The main hypothesis is that more significant beneficial metabolic effects will have specific life style counseling effect than conventional diet and exercise. The main purpose of this study is to assess above mentioned metabolic changes before and after 6-8 weeks of weight loss intervention.
The investigators will also study the following:
- The impact of life style counseling induced weight and/or fat loss on physical fitness
- The impact of life style counseling induced weight and/or fat loss on metabolic parameters (e.g. insulin sensitivity, lipid profile, ect.)
详细描述
I
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy Volunteers
- •BMI≥25 kg/m2
排除标准
- •Thyroid disease
- •Chronic diseases(rheumatic,liver, kidney, pulmonary, etc. diseases) have current signs or symptoms of severe, progressive or uncontrolled renal, hepatic, hematologic, gastrointestinal, endocrine, pulmonary, cardiac, neurologic, or cerebral disease, or diabetes;
- •chronic infections
- •show evidence of malignancy
- •be women who are pregnant, nursing
- •medical treatment except allergy medicines
- •tobacco, alcohol or drug addiction
研究组 & 干预措施
Conventional lifestyle counseling
Randomized, open label study to assess effect of 8 weeks of Conventional lifestyle counseling (low calorie diet and exercise) on body composition, physical fitness, and metabolic parameters
干预措施: Lifestyle Counseling (Behavioral)
Unconventional lifestyle counseling
Randomized, open label study to assess effect of 8 weeks of unconventional lifestyle counseling (low calorie "metabolic stairs" diet and circuit-based exercise) on body composition, physical fitness, and metabolic parameters
干预措施: Lifestyle Counseling (Behavioral)
结局指标
主要结局
A Body weight change after specific weight loss intervention
时间窗: 8 weeks
To assess the body composition changes (fat-free mass and fat mass (in kg)).
次要结局
- Metabolic parameters(8 weeks)
研究者
Adela Penesova, MD, PhD
Biomedical Center of Slovak Academy of Sciences, Institute of clinical and translational research
Slovak Academy of Sciences