跳至主要内容
临床试验/NCT03236168
NCT03236168已完成3 期

Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands

London School of Hygiene and Tropical Medicine1 个研究点 分布在 1 个国家目标入组 118 人开始时间: 2017年8月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
3 期
状态
已完成
入组人数
118
试验地点
1
主要终点
Number of Participants With Headlice

研究概览

简要总结

This is a pilot study evaluating if treatment for scabies also treats headlice in the same community

详细描述

Background:

Scabies and head lice are both ubiquitous ectoparasitic infections that have been identified as common public health problems in the Pacific Island Country Territories. Mass drug administration using ivermectin is increasingly recognised as an effective strategy for scabies treatment and control, however, its possible impact on prevalence of head lice has not been evaluated. Given that oral ivermectin is an effective treatment option for pediculosis capitis, we hypothesise that community treatment with ivermectin for scabies would also provide benefit by reducing prevalence of head lice infestation in the community. We aim to test this hypothesis with a small-scale pilot study in the Solomon Islands.

Methodology:

The study would be carried out at the Atoifi Adventist Hospital campus, on the North-Eastern coast of the island of Malaita. The campus houses an estimated 180 individuals and all residents would be invited to participate in the study and be offered treatment.

At baseline all individuals would undergo a standardized examination to collect data on the presence of scabies, impetigo and head lice. Following examination individuals would be weighed and given directly observed standard treatment for scabies.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • All participants living in the community will be offered treatment

排除标准

  • Patients with a contradindication to study medication
  • Patients unable to provide consent

研究组 & 干预措施

Intervention Arm

Other

This study consists of a single treatment arm. Patients will receive Ivermectin or where contraindicated (Pregnancy, Breastfeeding, Weight <15kg) Permethrin Cream and Malathion shampoo

干预措施: Ivermectin (Drug)

Intervention Arm

Other

This study consists of a single treatment arm. Patients will receive Ivermectin or where contraindicated (Pregnancy, Breastfeeding, Weight <15kg) Permethrin Cream and Malathion shampoo

干预措施: Permethrin 5% (Drug)

Intervention Arm

Other

This study consists of a single treatment arm. Patients will receive Ivermectin or where contraindicated (Pregnancy, Breastfeeding, Weight <15kg) Permethrin Cream and Malathion shampoo

干预措施: Malathion Shampoo 0.5% (Drug)

结局指标

主要结局

Number of Participants With Headlice

时间窗: 2 Weeks after treatment

Assessed in the study population by physical examination of hair

次要结局

  • Number of Participants With Headlice(3 Months after treatment)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验