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临床试验/NCT01067170
NCT01067170已完成不适用

The Effect of Pneumatic Compression Stockings on Hemodynamic Parameters in Hemodialysis Patients: A Randomized Crossover Trial

University of Calgary2 个研究点 分布在 1 个国家目标入组 51 人开始时间: 2008年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
51
试验地点
2
主要终点
Central blood volume

研究概览

简要总结

This study aims to determine the effect of pneumatic compression devices (PCDs) on central blood volume in hemodialysis patients. We hypothesize that PCDs will help maintain central blood volume, and therefore prevent sudden decreases in blood pressure during hemodialysis.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • on hemodialysis at least 3 months
  • on hemodialysis at least 3 times per week

排除标准

  • dialyzing with a central venous catheter
  • vascular access dysfunction
  • peripheral vascular disease
  • active medical issue
  • unable to provide informed consent

结局指标

主要结局

Central blood volume

时间窗: pre and post hemodialysis

次要结局

  • cardiac output(pre and post hemodialysis)
  • cardiac index(pre and post hemodialysis)
  • systemic vascular resistance(pre and post hemodialysis)
  • intracellular fluid volume(pre and post hemodialysis)
  • extracellular fluid volume(pre and post hemodialysis)
  • total body water(pre and post hemodialysis)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr Jennifer MacRae

Director, Hemodialysis and Vascular Access

University of Calgary

研究点 (2)

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