Comparative Study Between Three Different Modalities for Treatment of Inflammatory Punctal Stenosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Degree of patient satisfaction
研究概览
简要总结
This study aimed to compare the efficacy of three various modalities of treatment of inflammatory punctal stenosis (Punctal dilatation alone, combined punctal dilatation with topical medications, or peri-punctal injection of Triamcinolone acetonide)
详细描述
Acquired punctal stenosis is a condition in which the external opening of the lacrimal canaliculus, located in the nasal part of the palpebral margin, is narrowed or occluded. This condition results from chronic inflammation of the external punctum, leading to gradual fibrotic changes in the ostium, followed by progressive occlusion of the duct.
Different modalities were described for the treatment of acquired punctual stenosis. Repeated dilatation of the stenotic punctum is a simple procedure that may provide temporary improvement of the symptoms, but restenosis is common unless additional procedures are performed. Many other methods were used to augment punctual size, including 1-snip, 2-snip, and 3-snip punctoplasty, supplemented with adding sutures or Mini-Monoka insertion and punch punctoplasty.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 33 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age from 33 to
- •Both sexes.
- •Patients with inflammatory punctal stenosis or occlusion complaining of symptomatic epiphora.
排除标准
- •Subjects with previous lacrimal surgeries.
- •Subjects with lid margin malposition such as ectropion, entropion, or lid retraction.
- •Subjects with medial lid masses obscuring the punctum.
- •Subjects with a history of ocular trauma involving the medial aspect of the lid margin.
研究组 & 干预措施
Group A
Patients were treated with punctal dilatation only
干预措施: Punctal dilation (Procedure)
Group B
Patients were treated with a combination of punctual dilation and topical medication in the form of preservative-free steroid eye drops based on dexamethasone sodium phosphate (0.1%) and preservative-free artificial tears based on sodium hyaluronate, polyethylene, and propylene Glycol.
干预措施: Punctal dilation and topical medication (Drug)
Group C
Patients were treated with a peri-punctual injection of Triamcinolone acetonide.
干预措施: Triamcinolone acetonide (Drug)
结局指标
主要结局
Degree of patient satisfaction
时间窗: 3 months postoperatively
The degree of patient satisfaction was assessed using 3-point Likert Scale (1=Not satisfied, 2: No Difference, 3:Satisfied)
次要结局
- Punctal diameter(3 months postoperatively)
研究者
Yomna EL-Saied Mohamed Ibrahim
Resident of Ophthalmology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Tanta University