Effect of Pumpkin Seeds on the Dietary Fatty Acid Intake and Blood Pressure in Women
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Dietary fatty acid intake
研究概览
简要总结
The purpose of this study is to determine if the inclusion of 1.5 ounces of pumpkin seeds per day in the diet of women will alter dietary fatty acid intake or blood pressure.
详细描述
Cardiovascular disease is the number one cause of morbidity and mortality in United States. Diets high in polyunsaturated and monounsaturated fatty acids have been shown to decrease the risk of cardiovascular disease. Pumpkin seeds are a good source of monounsaturated and polyunsaturated fatty acids. Oil extracted from pumpkin seeds has been shown to lower blood pressure. One purpose of this study is to determine whether eating 1.5 ounces of pumpkin seeds per day will improve polyunsaturated and monounsaturated fatty acid intake in the diet in healthy adult women. Another purpose of this study is to determine whether eating 1.5 ounces of pumpkin seeds a day will lower blood pressure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Over the age of 18
- •Able to read, write, and speak English
- •Able to keep a three-day diet diary
- •Willing and able to consume pumpkin seeds
排除标准
- •Pregnant or planning to become pregnant
- •Allergic to pumpkin seeds
- •High blood pressure
- •Regularly consuming pumpkin seeds (more than 4 times per month)
- •Taking blood pressure medication
- •Liver disease
- •Kidney disease
- •Gastrointestinal disease
- •History of bariatric surgery
- •History of a major cardiovascular event
- •Heart disease
- •Currently undergoing cancer treatment (except nonmelanoma cancer)
- •Following a weight control diet
- •Following a disease specific diet
- •Following a vegan diet
- •Have a diagnosed eating disorder
结局指标
主要结局
Dietary fatty acid intake
时间窗: 12 weeks
The dietary fatty acid intake, specifically monounsaturated and polyunsaturated fatty acids, will be measured three times over the course of a twelve week period to determine if fatty acid intake changed during the intervention.
Blood pressure
时间窗: 12 weeks
Blood pressure will be measured at every meeting to determine if the addition of pumpkin seeds to the diet altered blood pressure.
次要结局
未报告次要终点