Effects of Aronia Berry on Oxidative Stress, Cholesterol, Blood Pressure and Semen Quality
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 109
- 试验地点
- 1
- 主要终点
- Cholesterol
研究概览
简要总结
Intervention cross-over study during which participants receive standardized amounts of aronia berry tablets or placebo for three months, then wash out for three months, then aronia tablets or placebo for three months. The potential health effects are investigated. Following parameters are measured before and after each period of tablet intake: 1) Blood pressure, 2) Lipid fractions, 3) Testosterone, 4) Phase II markers, 5) HbA1c, 6) HSCRP, 7) F2-isoprostanes, and 8) semen quality.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 65 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy men with total cholesterol between 5 and 7 mmol/L, who do not take medication
排除标准
- •Chronic diseases and intake of medication or antioxidants
研究组 & 干预措施
Aroia
干预措施: Aronia, washout and then placebo (Dietary Supplement)
Aroia
干预措施: Placebo, washout and then aronia (Dietary Supplement)
Placebo
干预措施: Aronia, washout and then placebo (Dietary Supplement)
Placebo
干预措施: Placebo, washout and then aronia (Dietary Supplement)
结局指标
主要结局
Cholesterol
时间窗: 9 months
HDL, LDL and total cholesterol in mmol/L
次要结局
- Phase II enzyme activity(9 months)
- Semen quality(9 months)
- Blood pressure(9 months)
- Isoprostanes(9 months)
- High Sensitivity C reactive protein(9 months)
研究者
Jens Fedder
Professor
Odense University Hospital