Acute effects of Electrical Stimulation on endothelium-dependent vasodilation and biochemical markers of healthy and cardiac

Faculdade de Ceilândia da Universidade de Brasília0 个研究点开始时间: 2018年3月31日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Inclusion criterias for healthy subjects were aged > 45 years; absence of previous history of disease or surgical procedure and functional alterations during initial assessment or found in anaminesis that may interfere with the assessment of FMD. The criterias for chagasic subjects were aged > 45 years; consistent symptoms with chagasic heart failure III-IV classes of New York Heart Association (NYHA); stable heart failure drug therapy; left ventricular ejection fraction < 45%.

•Exclusion criterias for healthy subjects were complications or cognitive/psychiatric disorders that hinder the realization of the protocol; electrical stimulation intolerance. The exclusion criterias for chagasic subjects were decompensated heart failure; uncontrolled diabetes; history of recent infection (last 03 months); corticosteroid use (last 03 months); valvular heart disease; unstable angina; acute myocardial infarction (last 03 months); obstructive hypertrophic cardiomyopathy; heart failure due to pericardial disease or corrected valvular disease; history of pulmonary / smoking disease (last 12 months); peripheral vascular disease; chronic use of oxygen therapy; previous implantation of a pacemaker or cardiac defibrillator; and systolic blood pressure at rest > 200 mmHg.

发起方

Faculdade de Ceilândia da Universidade de Brasília