NCT02023229已完成4 期
High-fiber High-fiber Diet and Branched Chain Aminoacids. Impact on Nutritional Status and Complications in Patients With Liver Cirrhosis
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran2 个研究点 分布在 1 个国家目标入组 68 人开始时间: 2011年1月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 68
- 试验地点
- 2
- 主要终点
- Nutritional status
研究概览
简要总结
Malnutrition is a frequent complication in patients with liver cirrhosis. Most patients have decreased dietary intake due to ascites, hepatic encephalopathy and pro-inflammatory cytokines.
We hypothesized that branched chain aminoacids can improve nutritional status and delay episodes of hepatic encephalopathy
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ambulatory patients Patients with confirmed diagnose of liver cirrhosis Patients classified as Child-Pugh A or Child Pugh B
排除标准
- •Acute or chronic renal failure Pregnancy Overt hepatic encephalopathy
结局指标
主要结局
Nutritional status
时间窗: At time of recruitment
Assessed by bioelectrical impedance vector analysis and mid-arm muscle circumference
次要结局
- Hepatic Encephalopathy(At time of recruitment)
研究者
ALDO TORRE DELGADILLO
Principal investigator
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
研究点 (2)
Loading locations...
相似试验
已完成
4 期
Enteral Nutrition in Liver CirrhosisLiver CirrhosisNCT00168961Charite University, Berlin, Germany
Unknown
4 期
Branched-chain Amino Acid (BCAA) on Progression of Advanced Liver DiseaseLiver CirrhosisNCT02837302Kyungpook National University Hospital1,470
招募中
不适用
The Influence of Nutritional Factors on the Prognosis of Liver Cirrhosis Patients and the Exploration of Predictive ModelsCirrhosisNCT06328517Juan Kang300
已完成
不适用
Hyperproteic Diet Plus Lactobacillus Reuteri and Nitazoxanide in Minimal Hepatic EncephalopathyMinimal Hepatic EncephalopathyHepatic CirrhosisNCT01135628Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran60
已完成
不适用
High-protein High-fiber Diet in Patients With Primary Biliary CirrhosisPrimary Biliary CirrhosisNCT01603199Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran36