DRKS00014558招募中1 期
Preoperative fractionated Stereotactic Radiosurgery for Breast Cancer (PROBE) - PROBE
Städtisches Klinikum Dessau0 个研究点目标入组 50 人开始时间: 2018年6月28日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 50 Years 至 one（—）
- 性别
- Female
入选标准
- •age = 50 years
- •Invasive ductal, monofocal carcinoma of the breast G1– G3, cT1c to cT2 (1 cm to 4 cm) without any evidence of lobular carcinoma or in situ DCIS (>10%)
- •Complete histological characterization including: ER expression status, PR expression status, Her-2/neu expression status, Ki-67 und PD-L1
- •no indication for preoperative chemotherapy
- •The patient is candidate for primary breast-conserving resection and sentinel lymph node biopsy.
- •Ability to understand protocol and ability and willingness to comply with follow-up
- •The patient agrees, that her case will be discussed repeatedly in interdisciplinary tumor boards.
- •Negative pregnancy test in premenopausal patients
- •If premenopausal and sexually active, maintained contraception for at least 12 months after radiotherapy
- •The patient agrees to have an Au-tissue marker placed to define localization oft the tumor.
排除标准
- •previous radiotherapy of affected breast
- •Pregnancy test positive
- •rheumatoide arthritis, systemic lupus erythematoides, scleroderma
- •breast implant of affected breast
- •Lack of tissue marker at the start of radiotherapy
- •Planned mastectomy or skin-sparing mastectomy
- •Planning constrains cannot be achieved (Drop-out after planning)
- •Inability to tolerate prone positioniong during radiotherapy.
研究者
相似试验
招募中
2 期
EO-TACTICS trialBrain metastaseJPRN-jRCTs042220014Mitsuya Koichi57
已完成
不适用
Stereotactic fractionated radiotherapy of the resection cavity as adjuvant treatment after resection of brain metastasesC71Malignant neoplasm of brainDRKS00009357niversitätsklinikum Freiburg, Klinik für Strahlenheilkunde60
招募中
不适用
Stereotactic Radiosurgery for Oligometastatic Cancers in Indian patientsCTRI/2022/01/039657Amrita Institute of Medical Sciences
已完成
2 期
Phase II study of stereotactic radiosurgery with volumetric modulated arc therapy for small lung cancerJPRN-UMIN000022855Department of Radiuation Oncology, Tohoku University Graduate School of Medicine21
尚未招募
4 期
Efficacy of stereotactic radiosurgery based on three-dimensional rotational angiography for cerebrovascular malformatioBrain arteriovenous malformationcerebrovascular disease, cerebrovascular malformationD002538JPRN-jRCT1032230589mekawa Motoyuki60