CTRI/2023/01/048707尚未招募不适用
Role of rTMS as an adjunctive treatment in treatment resistant OCD :A randomized double blind and sham control trial.
Dr Kartikeya R Singh1 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2023年1月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- To assess the efficacy of rTMS (Repetitive transcranial magnetic stimulation) as an adjunctive treatment modality in patients of treatment resistant OCD (Obsessive Compulsive Disorder
研究概览
简要总结
Repetitive transcranial magnetic stimulation is FDA approved treatment for Obsessive compulsive disorder. As the disorder causes significant distress and dysfunction study has not been done for resistant cases of OCD wich account for 30 % of total cases.This creates a gap in the management of resistant cases of OCD.
Our study is aimed at adjunctive treatment of resistant cases of OCD where the medications will not be changed during course of therapy and results will be analysed subsequently.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of either sex aged between 18 to 60 years.
- •Diagnosed cases of treatment resistant Obsessive compulsive disorder.
- •Normotensive patients.
- •Age range:- 18- 60 years Patients who gave written informed consent.
排除标准
- •Patients unwilling to participate in the study or dropped out during study period.
- •Current neurological or any comorbid psychiatric disorder.
- •History of epilepsy, significant head injury, drug abuse or any neurosurgical procedure, hypertension.
- •Subjects positive for TMS Adult Safety Screen (TASS) including individuals with cardiac pacemaker or metal in head.
- •Subjects who received ECT (Electro Convulsive Therapy) or antipsychotics in past 6 months.
结局指标
主要结局
To assess the efficacy of rTMS (Repetitive transcranial magnetic stimulation) as an adjunctive treatment modality in patients of treatment resistant OCD (Obsessive Compulsive Disorder
时间窗: Baseline and 2 weeks
次要结局
- To compare the efficacy of active low frequency rTMS as an adjunctive treatment with the sham rTMS in cases of treatment resistant OCD(To compare the efficacy of active low frequency rTMS as an adjunctive treatment with the sham rTMS in cases of treatment resistant OCD after 2 weeks)
研究者
研究点 (1)
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