Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 24
- 主要终点
- Dyspnea
研究概览
简要总结
The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.
详细描述
Nasal stimulation is generated by breathing, which enables olfaction and helps to rhythm brain activity. The loss of nasal stimulation in tracheotomized patients who are dependent on mechanical ventilation may negatively affect respiratory drive and contribute to dyspnea. Restoring nasal airflow therefore emerges as an attractive non-pharmacological approach to treat dyspnea in patients undergoing mechanical ventilation weaning.
The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Tracheostomy and mechanical ventilation
- •Consent to participate
- •Affiliation to health insurance
排除标准
- •Agitation, delirium
- •Continuous use of sedatives
- •Patients under law protection
- •Patients without health insurance
- •Breastfeeding and pregnancy
研究组 & 干预措施
Patients ventilated
Baseline ventilator settings under pressure support
干预措施: Baseline (Procedure)
Patients ventilated
Baseline ventilator settings under pressure support
干预措施: Installation of high flow humidified air cannula (Procedure)
Patients ventilated
Baseline ventilator settings under pressure support
干预措施: Nasal air puffs (Procedure)
Patients ventilated
Baseline ventilator settings under pressure support
干预措施: propeller fan (FAN) (Procedure)
结局指标
主要结局
Dyspnea
时间窗: minute 20
visual analogical scale
次要结局
- airway occlusion pressure(minute 20)
- end expiratory occlusion pressure(minute 20)
- respiratory electromyogram (EMG)(minute 20)
- tolerance(minute 20)