The degree of endothelial dysfunction caused by treatment of de novo coronary lesion with drug-coated balloon as compared to drug-eluting stent - The degree of endothelial dysfunction caused by treatment of de novo coronary lesion with drug-coated balloon as compared to drug-eluting stent (D5 study)

The luminal dimension in the treated segment did not differ between groups at the follow-up angiography. The vasoconstriction after acetylcholine infusion was less pronounced in the DCB arm than in the DES arm. The response to nitroglycerine did not differ between groups, suggesting that endothelial function in treated coronary vessels could be better preserved by DCB than by new-generation DES.