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临床试验/NCT04705064
NCT04705064Unknown不适用

Development and Prospective Validation of an Artificial Intelligence Model to Predict Postoperative Acute Kidney Injury

Seoul National University Hospital1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2021年3月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
2,000
试验地点
1
主要终点
the incidence of postoperative acute kidney injury

研究概览

简要总结

The main objective of this study is to develop and validate an artificial intelligence model that predicts postoperative acute kidney injury.

详细描述

Postoperative acute kidney injury is known to increase the length of hospital stay and healthcare cost. A lot of risk prediction models have been developed for identifying patients at increased risk of postoperative acute kidney injury. Recent advances in artificial intelligence make it possible to manage and analyze big data. Prediction model using an artificial intelligence and large-scale data can improve the accuracy of prediction performance. Furthermore, the use of an artificial intelligence may be a useful adjuvant tool in making clinical decisions or real-time prediction if it is integrated into the electrical medical record systems. However, before implementing an artificial intelligence model into the clinical setting, prospective evaluation of an artificial intelligence model's real performance is essential. However, to our knowledge, there was no artificial intelligence model for prediction of postoperative acute kidney injury, which was prospectively evaluated. Therefore, we aimed to develop an artificial intelligence model which predicts postoperative acute kidney injury and evaluate the model's performance prospectively.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults patients undergoing non-cardiac surgery

排除标准

  • Age under 18 years
  • Surgery duration < 1 hour
  • Transplantation surgery
  • Nephrectomy
  • Cardiac surgery
  • Patients who had severe kidney dysfunction preoperatively as follows:
  • Serum creatinine ≥ 4 mg/dl
  • Estimated glomerular filtration rate <15 ml/min/1.73m2
  • History of renal replacement therapy
  • Patients who had no results of preoperative or postoperative serum creatinine

结局指标

主要结局

the incidence of postoperative acute kidney injury

时间窗: during the postoperative seven days

postoperative acute kidney injury (diagnosed by KDIGO criteria using peak serum creatinine level) included all acute kidney injury events regardless of acute kidney injury severity

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hyung-Chul Lee

Assistant professor

Seoul National University Hospital

研究点 (1)

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