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临床试验/NCT04680663
NCT04680663已完成不适用

Peripheral Perfusion Index Versus Serum Lactate Levels as Predictor of Postoperative Complications and Prolonged ICU Stay After Lengthy Surgical Procedures: a Prospective Observational Study

Cairo University1 个研究点 分布在 1 个国家目标入组 235 人开始时间: 2021年3月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
235
试验地点
1
主要终点
Peripheral perfusion index

研究概览

简要总结

Many patients undergoing long time surgery will manifest increased level of blood lactate.

Hyperlactacidemia can cause disturbance of internal environment, then leading to increased complications and longer ICU stay, even death. For postoperative patients, we must ensure adequate perfusion in order to minimize the length of hyperglycemia and improve patients' outcomes. With regard to lactate, it provides information about prefusion, but not timely enough for its delay on reflecting hypoperfusion. And it's not real-time and non-invasive.

Peripheral perfusion index (PPI) is an indicator reflecting hypoperfusion in critical patients. It is measured using pulse co-oximetry technology which is characterized by being real-time and noninvasive. PPI is defined as "the ratio of pulsatile blood flow to the non-pulsatile blood flow", mirroring the strength of blood flow and quality of perfusion at sensor site, reflecting perfusion state of the body part . In contrast to lactate value, it's real-time and easy to monitor.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Peripheral perfusion index

时间窗: up to 48 hours

at end of surgery as early predictor of postoperative complications .

serum lactate level

时间窗: up do 48 hours

at end of surgery as early predictor of postoperative complications .

次要结局

  • serum lactate level(UP TO 30 day)
  • Peripheral perfusion index(UP TO 30 DAY)
  • Postoperative complications(up to 30 day)
  • hemodynamic change(up do 48 hours)
  • heart rate(up do 48 hours)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amr Samir Wahdan

Assistant Professor of Anesthesia, Pain management and Surgical ICU

Cairo University

研究点 (1)

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