Peripheral Perfusion Index Versus Serum Lactate Levels as Predictor of Postoperative Complications and Prolonged ICU Stay After Lengthy Surgical Procedures: a Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 235
- 试验地点
- 1
- 主要终点
- Peripheral perfusion index
研究概览
简要总结
Many patients undergoing long time surgery will manifest increased level of blood lactate.
Hyperlactacidemia can cause disturbance of internal environment, then leading to increased complications and longer ICU stay, even death. For postoperative patients, we must ensure adequate perfusion in order to minimize the length of hyperglycemia and improve patients' outcomes. With regard to lactate, it provides information about prefusion, but not timely enough for its delay on reflecting hypoperfusion. And it's not real-time and non-invasive.
Peripheral perfusion index (PPI) is an indicator reflecting hypoperfusion in critical patients. It is measured using pulse co-oximetry technology which is characterized by being real-time and noninvasive. PPI is defined as "the ratio of pulsatile blood flow to the non-pulsatile blood flow", mirroring the strength of blood flow and quality of perfusion at sensor site, reflecting perfusion state of the body part . In contrast to lactate value, it's real-time and easy to monitor.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Peripheral perfusion index
时间窗: up to 48 hours
at end of surgery as early predictor of postoperative complications .
serum lactate level
时间窗: up do 48 hours
at end of surgery as early predictor of postoperative complications .
次要结局
- serum lactate level(UP TO 30 day)
- Peripheral perfusion index(UP TO 30 DAY)
- Postoperative complications(up to 30 day)
- hemodynamic change(up do 48 hours)
- heart rate(up do 48 hours)
研究者
Amr Samir Wahdan
Assistant Professor of Anesthesia, Pain management and Surgical ICU
Cairo University
