Perioperative evaluation of transthoracic echocardiography derived left atrial strain using speckle-tracking: its correlation with transesophageal echocardiography derived diastolic dysfunction and postoperative adverse outcomes in elective off-pump coronary artery bypass graft surgery.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
研究概览
简要总结
This prospective observational study evaluates perioperative changes in 2D-speckle tracking echocardiography (STE) derived left atrial strain (LAS) in 40 patients undergoing elective off-pump CABG surgery. The study correlates preoperative Transthoracic Echocardiography (TTE)-derived LAS (reservoir, conduit, and contractile phases) with postoperative LAS values and intraoperative Transesophageal Echocardiography (TEE)-based diastolic dysfunction grading and explores its predictive value for postoperative adverse outcomes, including incidence of new-onset atrial fibrillation, low cardiac output syndrome, acute kidney injury, prolonged mechanical ventilation and low cardiac output syndrome.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 25.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients scheduled for elective isolated off-pump coronary artery bypass graft (CABG) surgery.
- •Sinus rhythm on preoperative electrocardiogram.
- •Adequate transthoracic echocardiographic windows for strain analysis.
- •Written informed consent.
排除标准
- •On-pump CABG surgery.
- •Combined valve and off-pump CABG surgery.
- •Previous cardiac surgery.
- •Severe mitral or aortic valve disease (moderate-severe or severe).
- •Congenital heart disease.
- •Severe left ventricular dysfunction (Ejection fraction less than 30 percent).
- •Severe pulmonary hypertension (Pulmonary Artery Systolic Pressure more than 60 mmHg).
- •Severe renal dysfunction.
- •(eGFR less than 30ml/min/1.73m2) Poor echocardiographic image quality precluding strain analysis.
研究者
Karan
Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi