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临床试验/NCT06245811
NCT06245811已完成不适用

Evaluation of the Relationship Between Hyperemesis Gravidarum (HEG) With Platelet Crit (PCT), Haemoglobin to Red Cell Distribution Width Ratio (HRR) and Neutrophil to Lymphocyte Ratio (NLR).

Izzet Celegen1 个研究点 分布在 1 个国家目标入组 215 人开始时间: 2022年1月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
215
试验地点
1
主要终点
The Pregnancy Unique Quantification of Emesis/Stomach scoring system

研究概览

简要总结

In this study, the relationship between the severity of hyperemesis gravidarum (HEG) disease and subclinical inflammatory factors such as Platelet Crit (PCT), Hemoglobin/red cell distribution width ratio (HRR), Neutrophil/lymphocyte ratio (NLR), was investigated.

详细描述

A total of 215 pregnant women, 102 with hyperemesis gravidarum and 113 healthy pregnant women, were included in the study. HEG patients were divided into three groups according to the modified PUQE classification: mild (n=38), moderate (n=32) and severe (n=32).

In our study, we proposed using a new prognostic marker for HEG patients. We think that our study will be a source for future studies on HEG.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Healthy pregnant women over 18 years of age
  • 5-16 weeks of gestation.

排除标准

  • Smoking, urinary tract infections, previously diagnosed psychological disorders, gastrointestinal disorders, multiple pregnancies, eating disorders, thyroid disorders, inflammatory disease, pregnancy with assisted fertilization technique.

结局指标

主要结局

The Pregnancy Unique Quantification of Emesis/Stomach scoring system

时间窗: 2 months

1: Weight loss of 5% or more since the beginning of pregnancy 2: Vomiting at least three times a day 3: A ketonuria value of +1 or higher on a urinalysis test

次要结局

  • Body mass index(2 months)

研究者

发起方
Izzet Celegen
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Izzet Celegen

Assistant professor

Yuzuncu Yıl University

研究点 (1)

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