EUCTR2016-001010-17-GB进行中（未招募）1 期
ucleos(t)ide withdrawal in HBeAg negative hepatitis B virus infection to promote HBsAg clearance. (NUC-B) - Nucleos(t)ide withdrawal in Hepatitis B virus infection (NUC-B)
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Chronic HBV infection
- •HBeAg negative
- •Nucleos(t)ide analogues treatment for =3 years
- •HBV DNA < 400 IU/ml =2 years
- •Informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 240
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 0
排除标准
- •Cirrhosis at any time
- •HBeAg to anti-HBe seroconversion within the last 3 years
- •Interferon use in the last 3 years
- •Contraindications to interferon use
- •Participation in HBV-specific therapeutic vaccine studies within 12 months
- •HCV, HDV or HIV co-infection
- •Immunosuppressant use
- •Clinically significant comorbidities that, in the opinion of the investigator, render the patient unsuitable.
研究者
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