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临床试验/NCT03073044
NCT03073044已完成不适用

Italian Validation of the Belastungfragebogen Parkinson Kurzversion (BELA-P-K): a Disease-specific Questionnaire for Evaluation of the Subjective Perception of Quality of Life.

Ospedale Generale Di Zona Moriggia-Pelascini0 个研究点目标入组 100 人开始时间: 2015年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
100
主要终点
Bela-p-K

研究概览

简要总结

The BELA-P-k was translated from Dutch into Italian. Subsequently 102 patients with PD filled out the questionnaire

详细描述

In order to provide an appropriate endpoint for the assessment of the effectiveness of rehabilitation treatments on QoL of PD patients, in this study we translated and then validated the Belastungsfragebogen Parkinson kurzversion (BELA-P-k). This tool allows evaluating separately two crucial aspects: i) the loss of personal autonomy in activities of daily life and ii) the psychological and psychosocial impact of the disease.

The BELA-P-k was translated from Dutch into Italian. Subsequently 102 patients with PD filled out the questionnaire. PD patients were also evaluated by using the Parkinson Disease Questionnaire -39 (PDQ39), the Unified Parkinson's Disease Rating Scale (UPDRS), the Mini Mental State Examination (MMSE) and the Frontal Assessment Battery (FAB) The internal consistency of the questionnaire was assessed by means of Cronbach's alpha coefficient.

The discriminant validity was assessed by testing for differences between mean values for patients grouped according to Hoehn and Yahr stages. This analysis was carried out by a one-way analysis of variance.

Finally, the construct validity was determined by assessing the relationship (Spearman rank correlation coefficient) between Bela-P-k and the PDQ39

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Parkinson's Disease

排除标准

  • any focal brain lesion detected in brain imaging studies (CT or MRI) performed in the previous twelve months;
  • other chronic diseases with a known impact in QoL.
  • MMSE < 24

结局指标

主要结局

Bela-p-K

时间窗: 15 minuts

questionnaire for QoL evaluation

次要结局

未报告次要终点

研究者

发起方
Ospedale Generale Di Zona Moriggia-Pelascini
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ilaria Zivi

Dipartimento di riabilitazione malattia di Parkinson, Disturbi del movimento e Cerebrolesioni Acquisite

Ospedale Generale Di Zona Moriggia-Pelascini

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