Exercise Capacity and Daily Physical Activity in Obese Subjects With Treated Obstructive Sleep Apnea
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Peak oxygen uptake (Peak VO2) measured at the end of the Incremental Shuttle Walk Test (ISWT)
研究概览
简要总结
Obesity is very common worldwide and breathing problems at night (obstructive sleep apnea, OSA) are common in obesity. Despite the best treatment, obesity and OSA are linked to early death from heart problems. They are also associated with lower levels of physical activity. Exercise strategies for weight loss, increasing physical activity and improving fitness are needed for obesity. In Obese individuals with OSA
- The investigators will compare corridor walking tests compared to laboratory exercise tests. The null hypothesis is that the peak oxygen uptake achieved and the cardiopulmonary response during both the six-minute walk test and Incremental Shuttle Walk Test would not be different from that observed during an Incremental Treadmill Test.
- The investigators will investigate whether cycling or walking uses more calories for the same intensity. We hypothesise that cycling (weight supported) will be endured for long.
- The investigators will compare commonly used exercise tests with levels of daily physical activity.
The information from these three projects will help us set up the optimal exercise program for obese individuals.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Obstructive Sleep Apnea
- •Obesity BMI>30
- •Controlled on Continuous Positive Airway Pressure for three months
排除标准
- •cardiac co-morbidity e.g ischaemic heart disease, chronic heart failure, valvular heart disease
- •pulmonary co-morbidity
- •neurological condition limiting the ability to perform walking or cycling
- •orthopaedic condition limiting the ability to perform walking or cycling
结局指标
主要结局
Peak oxygen uptake (Peak VO2) measured at the end of the Incremental Shuttle Walk Test (ISWT)
时间窗: All outcome measures will be performed within four weeks of each other
Two Incremental Shuttle Walk tests will be performed within two hours on the same day with expired gas analysis measured by a portable gas analyser. An ISWT is conducted over a 10m course and the speed is externally paced and increases each minute. The participant is asked to continue until they are either too breathless or too tired to continue.
次要结局
- Incremental Treadmill Test (ITM)(Four weeks)
- Endurance cycle ergometer(Four weeks)
- Endurance treadmill test(Four weeks)
- Daily physical activity(Four weeks)
- Six minute walk test (6MWT)(Four weeks)
- Incremental cycle test (ICE)(Four weeks)
研究者
Roger Goldstein
Respirologist
West Park Healthcare Centre