The Effect of Galvanic Stimulation on vHIT and VEMP Tests
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Cervical Vestibuler Evoked Myogenic Potentials
研究概览
简要总结
Introduction: Galvanic vestibular stimulation (GVS) is a well-established technique with a history spanning over a century, primarily used to manipulate the vestibular system. Recent interest has surged in its potential for understanding human vestibular function and aiding in functional recovery. GVS applies electrical currents to the mastoid region, modulating vestibular afferents, and induces specific effects based on the participant's posture and current polarity. While GVS's impact on the central nervous system and its potential to aid in functional recovery have been studied, its immediate effects on vestibular reflexes remain less explored.
Methods: In this study, thirty healthy adult participants underwent ocular and cervical vestibular evoked myogenic potential (VEMP) tests, as well as the velocity Head Impulse Test (vHIT) before and immediately after one hour of GVS application. Statistical analyses were performed to assess changes in VEMP and vHIT results.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 22 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •No history of hearing loss and/or balance disorders
- •No physical (neck) problems
- •No history of psychological or neurological disorders
- •Not using alcohol and/or vestibular suppressant drugs regularly
- •Feeling balanced in daily life
排除标准
- •History of hearing loss and/or balance disorders
- •Physical (neck) problems
- •History of psychological or neurological disorders
- •Using alcohol and/or vestibular suppressant drugs regularly
结局指标
主要结局
Cervical Vestibuler Evoked Myogenic Potentials
时间窗: 5 months
Vestibular evoked myogenic potentials (VEMPs) are muscle reflexes that occur in response to high-intensity acoustic stimuli delivered to the ear. These responses can be easily recorded using surface electrodes placed on the sternocleidomastoid muscle (SCM) or near the inferior oblique muscle .
Ocular Vestibuler Evoked Myogenic Potentials
时间窗: 5 months
Vestibular evoked myogenic potentials (VEMPs) are muscle reflexes that occur in response to high-intensity acoustic stimuli delivered to the ear. Ocular VEMP (oVEMP) recorded from surface electrodes placed under the eyes.
Video Head Impulse Test
时间窗: 5 months
The vestibulo-ocular reflex (VOR) is responsible for stabilizing images on the fovea during head movement. The velocity Head Impulse Test (vHIT) battery is a standard test for measuring head and eye movements, enabling the calculation of the gain of eye speed. The vHIT system typically employs light goggles to monitor eye position through cameras, along with a gyroscope to measure angular head movements, facilitating the computation of VOR gain.
次要结局
未报告次要终点
研究者
Berna Özge MUTLU
Principal Inverstigator
Istanbul Medipol University Hospital