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临床试验/NCT07166445
NCT07166445招募中不适用

Deep Learning for Automated Discrimination Between Stage T1-T2 and T3 Renal Cell Carcinoma on Contrast-Enhanced CT

Peking University First Hospital1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2024年9月1日最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
1,000
试验地点
1
主要终点
diagnostic performance

研究概览

简要总结

This study aims to develop and validate a contrast-enhanced CT-based deep-learning model for automatic and accurate preoperative discrimination between T1-T2 and T3 renal cell carcinoma. By quantifying the model's diagnostic performance on an independent test set-using AUC, sensitivity, specificity, positive/negative predictive values, and decision-curve analysis-we will establish a decision-support tool that can be seamlessly integrated into clinical PACS, thereby reducing staging errors, refining surgical planning, and improving patient outcomes.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Histopathologically confirmed renal cell carcinoma on postoperative specimen.
  • Preoperative contrast-enhanced CT performed at our institution with slice thickness ≤ 1 mm and complete DICOM datasets.
  • Postoperative pathologic staging clearly defined as pT1a-T2b or pT3a.
  • CT image quality deemed adequate for analysis.

排除标准

  • 1. Pathologic subtype other than RCC.
  • Images with severe artifacts.

结局指标

主要结局

diagnostic performance

时间窗: from 2024 to 2027

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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