NCT07166445招募中不适用
Deep Learning for Automated Discrimination Between Stage T1-T2 and T3 Renal Cell Carcinoma on Contrast-Enhanced CT
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- diagnostic performance
研究概览
简要总结
This study aims to develop and validate a contrast-enhanced CT-based deep-learning model for automatic and accurate preoperative discrimination between T1-T2 and T3 renal cell carcinoma. By quantifying the model's diagnostic performance on an independent test set-using AUC, sensitivity, specificity, positive/negative predictive values, and decision-curve analysis-we will establish a decision-support tool that can be seamlessly integrated into clinical PACS, thereby reducing staging errors, refining surgical planning, and improving patient outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 85 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Histopathologically confirmed renal cell carcinoma on postoperative specimen.
- •Preoperative contrast-enhanced CT performed at our institution with slice thickness ≤ 1 mm and complete DICOM datasets.
- •Postoperative pathologic staging clearly defined as pT1a-T2b or pT3a.
- •CT image quality deemed adequate for analysis.
排除标准
- •1. Pathologic subtype other than RCC.
- •Images with severe artifacts.
结局指标
主要结局
diagnostic performance
时间窗: from 2024 to 2027
次要结局
未报告次要终点
研究者
研究点 (1)
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