"Natural" and "Organic" Cigarette Descriptors: Association With Expectancies, Subjective Effects, Topography, and Biomarkers of Exposure Among Daily Smokers

University of Nevada, Reno6 个研究点分布在 1 个国家目标入组 184 人开始时间: 2022年1月20日最近更新: 2025年12月31日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: University of Nevada, Reno
入组人数: 184
试验地点: 6
主要终点: Difference in total puff volume relative to conventional condition - organic

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Smokers believe that cigarettes with the "natural" or "organic" descriptors are less harmful than cigarettes without these descriptors, but we do not know if these beliefs are associated with how smokers interpret the experience of smoking a "natural" or "organic" cigarette, nor whether these beliefs are predictive of changes in smoking behavior or biological exposures. The primary goal of this study is to examine the relationship between exposure to "natural" or "organic" descriptors in cigarette advertising and smoking health risk expectancies, subjective effects, topography, and biological exposures. To accomplish this goal, we will enroll 250 adult daily cigarette smokers of Natural American Spirit (NAS) or non-NAS brands (125 in each group) in a within-subjects human laboratory study manipulating four expectancy conditions (own brand comparator, "natural" advertising, "organic" advertising, "conventional" advertising).

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Other
盲法: None

入排标准

年龄范围: 21 Years 至 65 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Daily cigarette smoker of 5+ cigarettes/day for at least the past 6 months and consumed 100+ lifetime cigarettes
•Smoke non-menthol, filtered cigarettes
•Report daily use of any non-Natural American Spirit (NAS) cigarette brand for the last 30 days (for the non-NAS smoker group), or report daily use of NAS cigarettes for at least 30 days (for the NAS smoker group)
•Provide exhaled CO level >= 10 ppm at the Session 1 visit
•Able to communicate fluently in English (speaking, writing, and reading)
•Capable of providing written informed consent, which includes compliance with the requirements and restrictions listed in human participant protections

排除标准

•Current use of Nat's cigarettes as a preferred brand
•Plan to quit smoking in the next 30 days and not currently undergoing smoking cessation treatment
•Are pregnant, planning a pregnancy, and/or lactating
•Have any impairment including, but not limited to, visual, physical, and/or neurological impairments preventing the completion of procedures included within this protocol
•Have had a serious or unstable disease within the past 6 months (e.g. heart disease, cancer, schizophrenia).
•Cannot have ever regularly smoked NAS (for the non-NAS group)