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临床试验/NCT02630056
NCT02630056Unknown不适用

Validate the Dosimetric Parameters That Correlate With Acute Hematologic Toxicity (HT) in Patients With Rectal Cancer Treated With Neoadjuvant Chemoradiotherapy

Sixth Affiliated Hospital, Sun Yat-sen University0 个研究点目标入组 90 人开始时间: 2015年12月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
90
主要终点
the grade of acute hematologic toxicity

研究概览

简要总结

The purpose of this study is to validate the dosimetric parameters that correlate with acute hematologic toxicity (HT) in patients with rectal cancer treated with neoadjuvant chemoradiotherapy.

详细描述

The investigators' ongoing retrospective study investigated the clinical and dosimetric parameter (dosimetry of pelvic bone marrow) which relate with acute hematologic toxicity in patient with rectal cancer treated with neoadjuvant chemoradiotherapy. In order to validate the dosimetric limitation of pelvic bone marrow in decreasing the intensity of HT, the investigators want to conduct a study to observe the acute HT without assigning any specific interventions to the subjects of the study, who will receive the standard treatment according to the multidisciplinary team's (MDT) decision and patient choice. Therefore, this study's type is observational.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • rectal cancer
  • receive neoadjuvant chemoradiotherapy

排除标准

  • hematological system disorders

结局指标

主要结局

the grade of acute hematologic toxicity

时间窗: 5-6 weeks

Hematologic Adverse Events That Are Related to Pelvic Bone Marrow Irradiation

次要结局

未报告次要终点

研究者

发起方
Sixth Affiliated Hospital, Sun Yat-sen University
申办方类型
Other
责任方
Sponsor

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