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临床试验/NCT06730087
NCT06730087尚未招募不适用

Extravascular Lung Water and Fluid Responsiveness in Critically Ill Patient

Assiut University2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2024年12月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
80
试验地点
2
主要终点
electric cardiometry effectiveness in fluid management in critically ill patient

研究概览

简要总结

Assessment of validity of electrical cardiometry (EC) to measure fluid responsiveness and extravascular lung water that is expressed in the form of (thoracic fluid content) .

详细描述

  1. Study Setting:

The study will be conducted in Assiut University Hospital, in respiratory intensive care unit.

This study is a cross sectional design for Extravascular lung water and fluid responsiveness assessment in critically ill patient 2. Study subjects:

  1. Inclusion criteria:

  2. Patients who are 18 years old or more.

  3. patients will be divided into two groups: Group 1 patients with blood pressure less than 90/60 to assess fluid responsiveness and group 2 patients with sonographic finding of increase extravascular lung water in the form of interstitial edema or pulmonary edema or by electrical cardiometry (increase thoracic fluid content).

  4. Exclusion criteria:

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who are 18 years old or more.
  • patients will be divided into two groups: Group 1 patients with blood pressure less than 90/60 to assess fluid responsiveness and group 2 patients with sonographic finding of increase extravascular lung water in the form of interstitial edema or pulmonary edema or by electrical cardiometry (increase thoracic fluid content).

排除标准

  • Patients less than 18 years old.
  • Patients who refuse to participate in the study.

结局指标

主要结局

electric cardiometry effectiveness in fluid management in critically ill patient

时间窗: baseline

compairing fluid responsiveness by stroke vloume variation in carddiometry( Fluid responsiveness was defined as SVV \>10% to 15%) and IVC destinsability index by ultrasound (fluid rspnisveness was defined as \[(maximum IVC diameter on inspiration-minimum diameter on expiration)/minimum diameter on expiration\] \> 18%). compairing pulmonary edema by fluid thoracic content(normal range:25 to 35) in cardiometry and B lines in chest ultrasound(more than 3 b-lines in all 4 fields/BLUE points considered positive for pulmonary edema according to BLUE protocol).

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mostafa Mahmoud

lecturer assistant

Assiut University

研究点 (2)

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