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临床试验/CTRI/2018/02/012190
CTRI/2018/02/012190已完成4 期

Effect of preoperative chronic phenytoin versus levetiracetam therapyon neuromuscular block following atracurium or vecuronium

SCTIMST Hospital0 个研究点目标入组 40 人开始时间: 待定最近更新:

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1. ASA grade I or II undergoing neurosurgery under general
  • anesthesia.
  • 2. Age 18-60 years, of either sex, who have the ability to give informed consent.
  • 3. On chronic ( >7 days) phenytoin or levetiracetam therapy

排除标准

  • 1. Pre-existing neuromuscular disease
  • 2. Prolonged administration of neuromuscular blocker
  • 3. Any other drug known to affect neuromuscular function
  • 4. Peripheral neuropathies
  • 5. Prolonged immobility
  • 6. Following major burns upto 2 years
  • 7. Liver disease
  • 8. Kidney disease
  • 9. Cardiac disease
  • 10. Pregnancy
  • 11. Pre-existing or intraoperative acid-base disorder
  • 12. Electrolyte imbalances such as hyper/hypokalemia, hyper/hypocalcemia,
  • hyper/hypomagnesemia, hyper/hyponatremia
  • 13. Endocrinopathies
  • 14. Patient refusal

研究者

发起方
SCTIMST Hospital

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