Intensive lifestyle modification program on weight loss and metabolic syndrome risks among obese women in rural areas: a randomized control trial

Mahidol University0 个研究点目标入组 60 人开始时间: 2016年4月19日最近更新: 2024年8月19日

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•Inclusion criteria included age 30 to 50 years with a normal menstrual period, body mass index (BMI) â‰¥27.5 kg/m2, no chronic diseases, no drug use, no pregnancy, no breastfeeding, and no other weight loss program participation. From these eligible participants, 60 were randomly drawn and all agreed to join the program. Then, they were randomly assigned to either the intervention or the control group (1:1). A sample size calculation using the G*Power 3.1.7 statistical program indicated that a minimum of 25 participants were required using average triglyceride content data from previous studies with two independent groups, alpha (ï¡) 0.05, power (1-Î²) 0.9, and effect size 0.94 [16]. There were 30 participants in each group to allow for 20% of the expected drop-out rate.

•Exclusion criteria included age: <30 years old or >50 years old; BMI: <27.5 kg/m2; taking a medicine: antihypertensive, lipid lowering, psychiatric, steroid, and weight loss drugs or drugs involving metabolism; having underlying diseases: DM with taking hypoglycemic drugs , HT with taking antihypertensive drugs, thyroidism, coronary heart disease, psychiatric disorder, renal disease, cirrhosis; getting pregnancy or having pregnancy plan in the next 6 months; being in 6 months lactation period; participating in other weight loss programs

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