NL-OMON35087招募中不适用
Serum complement levels and the relation between zinc and Age-Related Macular Degeneration. - Zink supplementation in AMD
niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 51 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 51
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Men and women >= 50 years of age.
- •AMD patients previously included in the EUGENDA database.
- •Previously genotyped for Y402H (rs1061170) gene variation (from EUGENDA
- •Patients with extensive small drusen, intermediate drusen, large drusen, advanced
- •neovascular AMD without neovascular activity in one or both eyes or geographic
- •atropy in one or both eyes.
- •Informed consent.
排除标准
- •Active leakage from CNV due to AMD.
- •Ongoing anti/VEGF treatment.
- •Ongoing infection.
- •Subretinal hemorrhages.
- •History of any vitreous hemorrage within 12 weeks.
- •Other ocular disorders that may confound the interpretation of the study results.
- •Systemic or local steroid treatment within the last three months.
- •Use of any antibiotica.
- •Prolonged use of diuretics.
- •Supplemental use of iron (38-65 mg/day of elemental iron).
- •Use of zink and vitamin supplements one month prior to the study.
- •Systhemic diseases that may influence complement levels (atypical haemolytic
- •uraemic syndrome (aHUS), membranoproliferative glomerulonephritis type 2 (MG2)).
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