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临床试验/NCT04750733
NCT04750733已完成不适用

Impact of Core Performance on Functional Parameters in Multiple Sclerosis

Istanbul University - Cerrahpasa (IUC)1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2021年2月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
50
试验地点
1
主要终点
Core strength

研究概览

简要总结

Optimal trunk control relies on somatosensory, motor and musculoskeletal integrity, which is often damaged in multiple sclerosis (MS). Researches on postural control in people with MS (PwMS) have revealed that reduced somatosensory conduction may adversely affect some functions. PwMS have increased postural sway in upright posture than healthy people. They move closer and slower when reaching out or taking a step. Trunk controls are weak and postural responses are delayed. The activation of core muscles is very important for an effective trunk control. Because the core region is considered a kinetic link that facilitates the transfer of torque and angular momentum between the upper and lower extremities during body movements. The decrease in core stability affects both trunk control and the quality of limb movements due to the kinetic chain in the body. There are a limited number of studies in the literature showing that core stability is reduced in PwMS. Our knowledge about the effects of this reduction on function in PwMS is very limited.

详细描述

The aim of this study is to evaluate core strength and endurance and determine its effect on postural control, knee muscle strength, physical capacity and fatigue parameters in individuals with MS. Also relationship between these parameters will investigate.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Being diagnosed with MS according to McDonald's criteria
  • •Disability level less than 6 according to EDSS (Expanded Disability Status Scale) score
  • •No attacks during the last 3 months
  • •Being an ambulatory
  • •Volunteering to participate in the study

排除标准

  • •Having orthopedic, neurological, psychological, etc. diseases that accompany MS and may affect treatment outcomes
  • •Doing regular sports
  • •Being involved in another physiotherapy and rehabilitation program related to MS

结局指标

主要结局

Core strength

时间窗: Baseline

Core strength will be evaluated within the scope of core assessment. Curl-Up and Modified Push-Up test will be used for the evaluation of core strength.

Core endurance

时间窗: Baseline

Core endurance will be evaluated within the scope of core assessment. Trunk flexor, extensor, lateral endurance and plank will be used in the evaluation of core endurance and recorded as seconds.

Postural sway

时间窗: Baseline

Postural sways will be evaluated with biodex balance system in different condition such as open eyes on firm and foam surface, closed eyes on firm and foam surface, double stance on firm and foam surface, tandem stance on firm and foam surface.

İsokinetic strength

时间窗: Baseline

Concentric isokinetic muscle strength of the knee flexor and extensor muscles will be evaluated with Biodex isokinetic dynamometer at angular velocities of 30,60 and 90°/s.

次要结局

  • Physical capacity(Baseline)
  • Mobility(Baseline)
  • Fatigue(Baseline)

研究者

发起方
Istanbul University - Cerrahpasa (IUC)
申办方类型
Other
责任方
Principal Investigator
主要研究者

Feray Güngör

Physiotherapist, Research Assistant

Istanbul University - Cerrahpasa (IUC)

研究点 (1)

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