NCT00119990终止不适用
Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis; the Effect of Different Dialysates
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Changes in cardiac hemodynamics. (Cardiac Output, stroke volume, pulse rate, blood pressure and total peripheral resistance)
研究概览
简要总结
During peritoneal dialysis, water is removed from the body. This sometimes occurs at rates of up to 500 ml/h. During shifts with dialysate with high glucose content, an increase in blood pressure has been described. The effect upon central hemodynamics is unknown. The researchers are investigating the effects of low and high glucose dialysate and icodextrin on cardiac output, stroke volume, pulse rate and blood pressure. The researchers have hypothesized that the effects seen are induced by vasopressin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Peritoneal dialysis patients
排除标准
- •Insulin dependent diabetes mellitus
- •AV-fistula, cardial arrhythmia persistence, or severe cardiac and lung disease
- •Recent infectious disease
- •Severe psychiatric disease
- •Hypersensitivity to icodextrin
结局指标
主要结局
Changes in cardiac hemodynamics. (Cardiac Output, stroke volume, pulse rate, blood pressure and total peripheral resistance)
时间窗: 4 hours
次要结局
未报告次要终点
研究者
研究点 (2)
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