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临床试验/NCT00119990
NCT00119990终止不适用

Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis; the Effect of Different Dialysates

University of Aarhus2 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2006年1月1日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
终止
入组人数
15
试验地点
2
主要终点
Changes in cardiac hemodynamics. (Cardiac Output, stroke volume, pulse rate, blood pressure and total peripheral resistance)

研究概览

简要总结

During peritoneal dialysis, water is removed from the body. This sometimes occurs at rates of up to 500 ml/h. During shifts with dialysate with high glucose content, an increase in blood pressure has been described. The effect upon central hemodynamics is unknown. The researchers are investigating the effects of low and high glucose dialysate and icodextrin on cardiac output, stroke volume, pulse rate and blood pressure. The researchers have hypothesized that the effects seen are induced by vasopressin.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Peritoneal dialysis patients

排除标准

  • Insulin dependent diabetes mellitus
  • AV-fistula, cardial arrhythmia persistence, or severe cardiac and lung disease
  • Recent infectious disease
  • Severe psychiatric disease
  • Hypersensitivity to icodextrin

结局指标

主要结局

Changes in cardiac hemodynamics. (Cardiac Output, stroke volume, pulse rate, blood pressure and total peripheral resistance)

时间窗: 4 hours

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (2)

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