Can Antagonist Protocol be the Protocol of Choice in in Vitro Fertilization Patients?
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- number of oocytes collected and fertilized
研究概览
简要总结
The antagonist protocol in a novel method of stimulation in the in vitro fertilization (IVF) patients. It has been tried in poor responders, polycystic ovary (PCO) patients and normal females undergoing IVF. Can it be used with the same efficacy in all patients?
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 44 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •age: 20- 44 years
- •Poor responder females according to Bologna criteria
- •Polycystic ovarian disease females according to Rotterdam criteria
- •Females with infertility causes other than poor responders, or PCO; male factor or tubal block
排除标准
- •refusal to get enrolled in the study
- •cases of infertility due to severe male factor
研究组 & 干预措施
Normal
Human menopausal gonadotrophin IM daily was administrated from day 2 of the cycle. The Gonadotropins releasing hormone antagonist GnRH ant (Cetrotide, Serono, Geneva, Switzerland) was given when the leading follicle was from 12 to 14 mm, at a daily dose of 0.25 mg SC.
干预措施: Gonadotropins releasing hormone antagonist (Drug)
Poor responders
Human menopausal gonadotrophin IM daily was administrated from day 2 of the cycle. The Gonadotropins releasing hormone antagonist GnRH ant (Cetrotide, Serono, Geneva, Switzerland) was given when the leading follicle was from 12 to 14 mm, at a daily dose of 0.25 mg SC
干预措施: Gonadotropins releasing hormone antagonist (Drug)
Polycystic ovarian disease
Human menopausal gonadotrophin IM daily was administrated from day 2 of the cycle. The Gonadotropins releasing hormone antagonist GnRH ant(Cetrotide, Serono, Geneva, Switzerland) was given when the leading follicle was from 12 to 14 mm, at a daily dose of 0.25 mg SC
干预措施: Gonadotropins releasing hormone antagonist (Drug)
结局指标
主要结局
number of oocytes collected and fertilized
时间窗: 6 months
次要结局
未报告次要终点
研究者
Dina Mohamed Refaat Dakhly
lecturer of obstetrics and gynecology
Woman's Health University Hospital, Egypt