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临床试验/NCT06621485
NCT06621485已完成不适用

Multi-institutional Development and Validation of an Individualized Online Calculator for Early Mortality Risk After Hepatectomy Among Patients With Hepatocellular Carcinoma

Beijing Tsinghua Chang Gung Hospital1 个研究点 分布在 1 个国家目标入组 4,966 人开始时间: 2024年2月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
4,966
试验地点
1
主要终点
90-day death

研究概览

简要总结

Using the multicenter data, we developed and validated an individualized online calculator to predict early mortality after liver resection for hepatocellular carcinoma. The user-friendly tool with 6 preoperative predictors demonstrated excellent accuracy. The freely available calculator may help identify high-risk patients and reduce futile liver resection for hepatocellular carcinoma.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults (age ≥18 years) who underwent curative-intent hepatectomy for newly diagnosed HCC.
  • HCC diagnosis was confirmed histopathologically.

排除标准

  • Patients undergoing emergency hepatectomy for tumor rupture, as well as individuals with recurrent HCC, and those with missing survival data or less than 90 days of follow-up were excluded.

结局指标

主要结局

90-day death

时间窗: The period starts from the day of the hepatectomy surgery and extends up to the 90th day post-surgery.

90-day mortality after hepatectomy for HCC

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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