Carbetocin Versus Oxytocin in Caesarean Section: A Comparative study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 230
- 试验地点
- 1
- 主要终点
- To calculate the proportion of women in each group with need of additional uterotonics within 24 hours of delivery
研究概览
简要总结
The theme of the study is to compare the effectiveness of carbetocin vs oxytocin as a uterotonic in preventing PPH post caesarean delivery. The primary outcome is to calculate the proportion of women in each group with need of additional uterotonics. The secondary outcomes are to measure e****stimated blood loss, difference in preop and post Hemoglobin. vitals gins during and after the operation, uterine tone and uterine contractility. If the efficacy of Carbetocin is proven over Oxytocin as a superior uterotonic, Carbetocin can be drug of choice for prevention and control of PPH hence impacting the Maternal Mortality rate and the reduction of maternal deaths in India. Current studies have been ineffective in comparing the efficacy of both drugs hence further studies are needed to compare the efficacy of both drugs as uterotonics in preventing PPH after caesarean delivery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Female
入选标准
- •1 Previous Caesarean Delivery 2 Fetal Macrosomia 3 Malpresentation.
排除标准
- •1 Multiple gestation 2 Placenta previa and placental abruption 3 Uterine fibroids 4 Bronchial asthma 5 Cardiac disease 6 Epilepsy Hypertension Liver, renal or endocrine disease Women with hypersensitivity to carbetocin.
结局指标
主要结局
To calculate the proportion of women in each group with need of additional uterotonics within 24 hours of delivery
时间窗: 24 hours post delivery
次要结局
- Estimated blood loss, difference in preop & post Hemoglobin ,vitals ,signs during & after the operation, uterine tone & uterine contractility(24 hours before delivery & 24 hours post delivery)
研究者
Dr Anirudh Sood
Kasturba Medical College,Manipal